Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADRA2CAdrenoceptor alpha 2C. (428 aa)    
Predicted Functional Partners:
gng2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.914
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.914
ENSACLP00000020432
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.907
gnb4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
  0.907
gnb3
Guanine nucleotide binding protein (G protein), beta polypeptide 3a.
    
  0.907
LOC113013061
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
    
 0.902
gnai2
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
    
 0.902
ENSACLP00000035792
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.
    
 0.902
gnb5
Guanine nucleotide binding protein (G protein), beta 5a.
    
  0.890
LOC113022298
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
    
  0.890
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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