Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)    
Predicted Functional Partners:
atg3
Autophagy-related protein 3.
   
 0.999
atg12
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
   
 0.999
atg16l1
ATG16 autophagy related 16-like 1 (S. cerevisiae).
   
 0.997
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae).
    
 0.997
ENSACLP00000009003
Autophagy_act_C domain-containing protein.
    
 0.994
ENSACLP00000015189
WD_REPEATS_REGION domain-containing protein.
   
 0.994
map1lc3a
Microtubule-associated protein 1 light chain 3 alpha.
    
 0.986
map1lc3b
Microtubule-associated protein 1 light chain 3 beta.
    
 0.986
wipi2
WD repeat domain, phosphoinositide interacting 2.
    
 0.981
mavs
CARD_2 domain-containing protein.
    
 0.980
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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