Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
gpc2Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (586 aa)    
Predicted Functional Partners:
LOC113021803
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
   
 
 0.897
fzd4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.852
LOC113031828
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.837
LOC113034822
Heparin-binding EGF-like growth factor a.
    
  0.819
ENSACLP00000010316
Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.800
fzd10
Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.800
fzd3
Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.769
FZD3
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.769
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
   
 
 0.762
LOC113011338
Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.757
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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