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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000006066BUB3 mitotic checkpoint protein. (324 aa)    
Predicted Functional Partners:
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 0.996
cdc27
Cell division cycle 27.
    
 0.996
anapc4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.993
ENSACLP00000008361
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.992
ENSACLP00000008418
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.992
ENSACLP00000018094
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.988
ENSACLP00000018067
BUB1 N-terminal domain-containing protein.
   
 0.987
LOC113007418
RAN binding protein 2.
   
 
 0.986
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
   
 0.983
anapc5
Anaphase promoting complex subunit 5.
    
 0.981
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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