Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACLP00000006066BUB3 mitotic checkpoint protein. (324 aa)    
Predicted Functional Partners:
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 0.999
ENSACLP00000008361
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.998
ENSACLP00000008418
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.998
cdc27
Cell division cycle 27.
    
 0.998
anapc5
Anaphase promoting complex subunit 5.
    
 0.998
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
   
 0.998
anapc4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.997
cdc16
Cell division cycle 16 homolog (S. cerevisiae).
   
 0.997
ENSACLP00000018067
BUB1 N-terminal domain-containing protein.
   
 0.996
ENSACLP00000018094
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.996
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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