Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113009051Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (939 aa)    
Predicted Functional Partners:
ENSACLP00000033830
Integrin beta.
   
 0.985
LOC113010138
Integrin beta; Belongs to the integrin beta chain family.
   
 0.951
itgb1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.951
LAMA2
Laminin subunit alpha 2.
    
 0.924
lamb3
Uncharacterized protein.
   
 0.920
itgb8
Integrin beta; Belongs to the integrin beta chain family.
    
 0.917
LOC113008411
Integrin beta.
   
 0.911
LAMC2
Laminin subunit gamma 2.
    
 0.908
ENSACLP00000031964
Integrin beta; Belongs to the integrin beta chain family.
   
 0.907
LOC113031147
Vitronectin b.
    
 0.894
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: medium (42%) [HD]