Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACLP00000006112Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. (2373 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.932
ENSACLP00000026055
Calcium channel, voltage-dependent, N type, alpha 1B subunit, a.
  
  
 
0.922
ENSACLP00000040753
Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.
  
  
 
0.922
cacna2d2
Calcium channel, voltage-dependent, alpha 2/delta subunit 2a.
   
 0.880
LOC113022409
Calcium channel, voltage-dependent, alpha 2/delta subunit 2b.
   
 0.880
LOC113008780
Calcium channel, voltage-dependent, alpha 2/delta subunit 1a.
   
 0.880
ENSACLP00000036840
Calcium voltage-gated channel auxiliary subunit alpha2delta 1.
   
 0.880
rasgrf2
Ras protein-specific guanine nucleotide-releasing factor 2b.
   
 
  0.873
ENSACLP00000035057
Ras protein-specific guanine nucleotide-releasing factor 2a.
   
 
  0.873
RASGRP2
RAS guanyl releasing protein 2.
     
  0.871
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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