Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
creld2Cysteine-rich with EGF-like domains 2. (361 aa)    
Predicted Functional Partners:
manf
Mesencephalic astrocyte-derived neurotrophic factor.
   
  
 0.960
ENSACLP00000016982
J domain-containing protein.
   
 
 0.915
dnajb11
DnaJ heat shock protein family (Hsp40) member B11.
   
 
 0.915
hyou1
Hypoxia up-regulated 1.
   
 
 0.887
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
  
 0.849
sdf2
Stromal cell-derived factor 2.
   
 
 0.831
sdf2l1
Stromal cell-derived factor 2-like 1.
   
 
 0.831
gmppb
GDP-mannose pyrophosphorylase B.
   
  
 0.820
ENSACLP00000018666
NTP_transferase domain-containing protein.
   
  
 0.820
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
  
 0.726
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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