Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113032538Sphingomyelin phosphodiesterase 5. (576 aa)    
Predicted Functional Partners:
smpd4
Sphingomyelin phosphodiesterase 4.
     
 0.955
smpd2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
     
 0.933
ENSACLP00000017287
Ceramide synthase 6.
     
 0.921
smpd1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
     
 0.917
ENSACLP00000020536
Zgc:153896.
     
 0.904
ENSACLP00000000091
Ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 2.
     
 0.903
ENSACLP00000029668
Ectonucleotide pyrophosphatase/phosphodiesterase 7.
     
 0.903
ENSACLP00000025365
Neutral ceramidase.
     
 0.900
cers5
Ceramide synthase 5.
     
 0.893
CERS5
Ceramide synthase 5.
     
 0.893
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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