Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CTSZCathepsin Z; Belongs to the peptidase C1 family. (303 aa)    
Predicted Functional Partners:
LOC113033302
Cathepsin F; Belongs to the peptidase C1 family.
   
 0.894
ENSACLP00000015540
Cathepsin O; Belongs to the peptidase C1 family.
    
 0.892
LOC113028579
Baculoviral IAP repeat containing 5a.
     
 0.889
LOC113024174
Cathepsin Ba; Belongs to the peptidase C1 family.
   
 0.884
LOC113006510
Cathepsin Bb; Belongs to the peptidase C1 family.
   
 0.884
bcl2l1
BCL2 like 1.
     
 0.883
LOC113023368
Carboxypeptidase; Belongs to the peptidase S10 family.
   
 0.876
CTSH
Cathepsin H; Belongs to the peptidase C1 family.
   
 0.876
ctsa
Carboxypeptidase; Belongs to the peptidase S10 family.
   
 0.876
ENSACLP00000030327
Cathepsin H; Belongs to the peptidase C1 family.
   
 0.876
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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