tnk1 protein (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

tnk1

Tyrosine kinase, non-receptor, 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (731 aa)

Predicted Functional Partners:

grb2

0.947

LOC113022989

0.879

nck2

0.818

nck1

0.818

cltcl1

0.756

ENSACLP00000038202

0.756

LOC113024435

0.709

ENSACLP00000011894

0.709

LOC113021048

0.709

LOC113020258

0.709

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000011894	ENSACLP00000038202	ENSACLP00000011894	ENSACLP00000038202	GRB2 related adaptor protein 2b.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.428
ENSACLP00000011894	cltcl1	ENSACLP00000011894	ENSACLP00000015217	GRB2 related adaptor protein 2b.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.428
ENSACLP00000011894	grb2	ENSACLP00000011894	ENSACLP00000027361	GRB2 related adaptor protein 2b.	Growth factor receptor-bound protein 2b.	0.693
ENSACLP00000011894	nck1	ENSACLP00000011894	ENSACLP00000040621	GRB2 related adaptor protein 2b.	Cytoplasmic protein.	0.495
ENSACLP00000011894	nck2	ENSACLP00000011894	ENSACLP00000003239	GRB2 related adaptor protein 2b.	Cytoplasmic protein.	0.495
ENSACLP00000011894	tnk1	ENSACLP00000011894	ENSACLP00000006215	GRB2 related adaptor protein 2b.	Tyrosine kinase, non-receptor, 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.709
ENSACLP00000038202	ENSACLP00000011894	ENSACLP00000038202	ENSACLP00000011894	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	GRB2 related adaptor protein 2b.	0.428
ENSACLP00000038202	LOC113020258	ENSACLP00000038202	ENSACLP00000030912	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.428
ENSACLP00000038202	LOC113021048	ENSACLP00000038202	ENSACLP00000013334	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	GRB2 related adaptor protein a.	0.428
ENSACLP00000038202	LOC113022989	ENSACLP00000038202	ENSACLP00000036531	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Cell division cycle 42.	0.628
ENSACLP00000038202	LOC113024435	ENSACLP00000038202	ENSACLP00000001130	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	GRB2 related adaptor protein b.	0.428
ENSACLP00000038202	cltcl1	ENSACLP00000038202	ENSACLP00000015217	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.938
ENSACLP00000038202	grb2	ENSACLP00000038202	ENSACLP00000027361	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Growth factor receptor-bound protein 2b.	0.621
ENSACLP00000038202	nck1	ENSACLP00000038202	ENSACLP00000040621	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Cytoplasmic protein.	0.463
ENSACLP00000038202	nck2	ENSACLP00000038202	ENSACLP00000003239	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Cytoplasmic protein.	0.463
ENSACLP00000038202	tnk1	ENSACLP00000038202	ENSACLP00000006215	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Tyrosine kinase, non-receptor, 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.756
LOC113020258	ENSACLP00000038202	ENSACLP00000030912	ENSACLP00000038202	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.428
LOC113020258	cltcl1	ENSACLP00000030912	ENSACLP00000015217	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.428
LOC113020258	grb2	ENSACLP00000030912	ENSACLP00000027361	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.693
LOC113020258	nck1	ENSACLP00000030912	ENSACLP00000040621	Uncharacterized protein.	Cytoplasmic protein.	0.495

page 1 of 5

Server load: low (20%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About