Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC113012724MYCL proto-oncogene, bHLH transcription factor a. (369 aa)    
Predicted Functional Partners:
ENSACLP00000031450
MYCN proto-oncogene, bHLH transcription factor.
    
 0.675
trip12
Thyroid hormone receptor interactor 12.
    
   0.630
ENSACLP00000004744
Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
     
 0.610
ENSACLP00000010760
Aspartate dehydrogenase domain containing.
      
 0.602
tfdp1
Transcription factor.
    
  0.596
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
      
 0.590
YAF2
YY1 associated factor 2.
    
 0.561
LOC113009167
YY1 associated factor 2.
    
 0.561
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 0.542
LOC113014387
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
 0.542
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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