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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC113012724MYCL proto-oncogene, bHLH transcription factor a. (369 aa)    
Predicted Functional Partners:
ENSACLP00000031450
MYCN proto-oncogene, bHLH transcription factor.
    
0.723
srebf2
Sterol regulatory element binding transcription factor 2.
    
 0.654
srebf1
Sterol regulatory element binding transcription factor 1.
    
 0.654
tfdp1
Transcription factor.
    
  0.641
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 0.624
LOC113014387
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
 0.624
LOC113032794
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
 0.624
RING1
Ring finger protein 1.
    
 0.583
ENSACLP00000033001
Ring finger protein 2.
    
 0.583
sirt6
Sirtuin 6.
    
 0.573
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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