Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (599 aa)    
Predicted Functional Partners:
ENSACLP00000036496
Spindle and kinetochore associated complex subunit 2.
     
  0.839
ska1
Spindle and kinetochore associated complex subunit 1.
   
 
  0.831
SGO1
Shugoshin_C domain-containing protein.
   
 
 0.783
KIF18A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
  0.721
ENSACLP00000013937
Centromere protein F.
   
 
  0.704
ENSACLP00000028406
NDC80 kinetochore complex component.
   
 
 0.703
ENSACLP00000026460
Cytoskeleton associated protein 5.
     
 0.700
ercc6l
Excision repair cross-complementation group 6-like.
   
 
  0.691
mad1l1
Mitotic arrest deficient 1 like 1.
     
 0.668
ENSACLP00000030315
Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
  0.667
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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