Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC113024494Fascin. (492 aa)    
Predicted Functional Partners:
espn
Espin.
    
 0.703
espnl
Espin like a.
    
 0.703
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
     
 0.543
ebi3
Epstein-Barr virus induced 3.
      
 0.488
rfc4
Replication factor C (activator 1) 4.
    
   0.480
RPS27A
Ribosomal protein S27a.
    
   0.480
GRXCR2
Glutaredoxin and cysteine rich domain containing 2.
     
 0.471
LOC113012109
Plastin 1 (I isoform).
     
 0.469
LOC113030625
Plastin 3.
     
 0.469
ENSACLP00000017444
Xin actin binding repeat containing 2b.
    
 0.469
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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