Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113016981Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (284 aa)    
Predicted Functional Partners:
F2RL3
F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
  0.729
LOC113032936
Coagulation factor II (thrombin) receptor-like 2.
    
  0.728
casp7
Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.705
ENSACLP00000022919
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
  0.700
f2rl1
Coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1.
    
  0.697
LOC113025430
Coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2.
    
  0.697
LOC113014939
Uncharacterized protein; Belongs to the intermediate filament family.
    
  0.690
lmna
Lamin A; Belongs to the intermediate filament family.
    
  0.690
lmnb2
Lamin B2; Belongs to the intermediate filament family.
    
  0.690
LOC113008263
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
  0.689
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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