Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gsk3bGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (425 aa)    
Predicted Functional Partners:
ENSACLP00000007241
Uncharacterized protein.
    
 0.992
axin1
Axin 1.
    
 0.992
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.991
AXIN2
Axin 2.
    
 0.989
LOC113020813
Axin 2 (conductin, axil).
    
 0.989
apc2
APC regulator of WNT signaling pathway 2.
    
 0.977
ENSACLP00000022635
Glycogen synthase kinase binding protein.
    
 0.977
ENSACLP00000028679
APC regulator of WNT signaling pathway.
    
 0.977
LOC113014539
Uncharacterized protein.
    
 0.971
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
    
 0.965
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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