STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gsk3bGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (425 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.983
ENSACLP00000022635
Glycogen synthase kinase binding protein.
    
 0.976
AXIN2
Axin 2.
   
 0.971
LOC113020813
Axin 2 (conductin, axil).
   
 0.971
ENSACLP00000007241
Uncharacterized protein.
   
 0.969
axin1
Axin 1.
   
 0.969
LOC113014539
Uncharacterized protein.
    
 0.963
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
0.937
LOC113030100
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
0.937
akt2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
0.937
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.