Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
esm1Endothelial cell-specific molecule 1. (181 aa)    
Predicted Functional Partners:
cdh5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.731
ENSACLP00000001612
Apelin.
      
 0.638
LOC113027822
Growth differentiation factor 2.
    
 
 0.623
ENSACLP00000035615
Uncharacterized protein.
    
 0.609
ENSACLP00000035628
Interleukin-1.
    
 0.609
tnfrsf13b
TACI-CRD2 domain-containing protein.
    
 0.575
rbpj
Recombination signal binding protein for immunoglobulin kappa J region.
      
 0.534
ENSACLP00000017664
Recombination signal binding protein for immunoglobulin kappa J region a.
      
 0.534
LOC113015119
Stathmin; Belongs to the stathmin family.
    
 
 0.527
mesd
Mesoderm development LRP chaperone.
      
 0.517
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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