cdc123 protein (Astatotilapia calliptera) - STRING interaction network

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cdc123

Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family. (341 aa)

Predicted Functional Partners:

eif2s2

0.976

eif2s3

0.963

ENSACLP00000006416

0.936

eif2s1

0.909

eefsec

0.824

RNF8

0.790

cops5

0.764

c7h11orf58

0.746

cdkal1

0.721

wdfy2

0.711

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000006416	RNF8	ENSACLP00000006416	ENSACLP00000035704	Nudix (nucleoside diphosphate linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.419
ENSACLP00000006416	cdc123	ENSACLP00000006416	ENSACLP00000006485	Nudix (nucleoside diphosphate linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.936
RNF8	ENSACLP00000006416	ENSACLP00000035704	ENSACLP00000006416	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Nudix (nucleoside diphosphate linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family.	0.419
RNF8	cdc123	ENSACLP00000035704	ENSACLP00000006485	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.790
c7h11orf58	cdc123	ENSACLP00000033439	ENSACLP00000006485	Zgc:56106.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.746
cdc123	ENSACLP00000006416	ENSACLP00000006485	ENSACLP00000006416	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Nudix (nucleoside diphosphate linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family.	0.936
cdc123	RNF8	ENSACLP00000006485	ENSACLP00000035704	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.790
cdc123	c7h11orf58	ENSACLP00000006485	ENSACLP00000033439	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Zgc:56106.	0.746
cdc123	cdkal1	ENSACLP00000006485	ENSACLP00000020396	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	CDK5 regulatory subunit associated protein 1-like 1.	0.721
cdc123	cops5	ENSACLP00000006485	ENSACLP00000038361	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	COP9 signalosome subunit 5.	0.764
cdc123	eefsec	ENSACLP00000006485	ENSACLP00000036270	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Eukaryotic elongation factor, selenocysteine-tRNA-specific.	0.824
cdc123	eif2s1	ENSACLP00000006485	ENSACLP00000036230	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.909
cdc123	eif2s2	ENSACLP00000006485	ENSACLP00000031404	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Eukaryotic translation initiation factor 2, subunit 2 beta.	0.976
cdc123	eif2s3	ENSACLP00000006485	ENSACLP00000021948	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	Eukaryotic translation initiation factor 2, subunit 3 gamma.	0.963
cdc123	wdfy2	ENSACLP00000006485	ENSACLP00000031046	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	WD repeat and FYVE domain containing 2.	0.711
cdkal1	cdc123	ENSACLP00000020396	ENSACLP00000006485	CDK5 regulatory subunit associated protein 1-like 1.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.721
cops5	cdc123	ENSACLP00000038361	ENSACLP00000006485	COP9 signalosome subunit 5.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. Belongs to the CDC123 family.	0.764
cops5	eefsec	ENSACLP00000038361	ENSACLP00000036270	COP9 signalosome subunit 5.	Eukaryotic elongation factor, selenocysteine-tRNA-specific.	0.521
cops5	eif2s1	ENSACLP00000038361	ENSACLP00000036230	COP9 signalosome subunit 5.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.730
cops5	eif2s2	ENSACLP00000038361	ENSACLP00000031404	COP9 signalosome subunit 5.	Eukaryotic translation initiation factor 2, subunit 2 beta.	0.643

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