ENSACLP00000006507 protein (Astatotilapia calliptera)

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Score

ENSACLP00000006507

Uncharacterized protein. (259 aa)

Predicted Functional Partners:

ENSACLP00000006491

0.900

ENSACLP00000006546

0.899

ENSACLP00000006557

0.899

RNF8

0.875

ENSACLP00000013582

0.839

UBE3A

0.812

ENSACLP00000009816

0.806

LOC113007418

0.774

LOC113018712

0.765

mapk6

0.747

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000006491	ENSACLP00000006507	ENSACLP00000006491	ENSACLP00000006507	Hect domain and RLD 7.	Uncharacterized protein.	0.900
ENSACLP00000006491	ENSACLP00000006546	ENSACLP00000006491	ENSACLP00000006546	Hect domain and RLD 7.	Uncharacterized protein.	0.896
ENSACLP00000006491	ENSACLP00000006557	ENSACLP00000006491	ENSACLP00000006557	Hect domain and RLD 7.	HECT domain-containing protein.	0.592
ENSACLP00000006491	ENSACLP00000009816	ENSACLP00000006491	ENSACLP00000009816	Hect domain and RLD 7.	Neuralized E3 ubiquitin protein ligase 4.	0.806
ENSACLP00000006491	ENSACLP00000013582	ENSACLP00000006491	ENSACLP00000013582	Hect domain and RLD 7.	Uncharacterized protein.	0.839
ENSACLP00000006491	LOC113007418	ENSACLP00000006491	ENSACLP00000030257	Hect domain and RLD 7.	RAN binding protein 2.	0.774
ENSACLP00000006491	LOC113018712	ENSACLP00000006491	ENSACLP00000007040	Hect domain and RLD 7.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.765
ENSACLP00000006491	RNF8	ENSACLP00000006491	ENSACLP00000035704	Hect domain and RLD 7.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.875
ENSACLP00000006491	UBE3A	ENSACLP00000006491	ENSACLP00000010931	Hect domain and RLD 7.	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	0.812
ENSACLP00000006491	mapk6	ENSACLP00000006491	ENSACLP00000027932	Hect domain and RLD 7.	Mitogen-activated protein kinase 6.	0.747
ENSACLP00000006507	ENSACLP00000006491	ENSACLP00000006507	ENSACLP00000006491	Uncharacterized protein.	Hect domain and RLD 7.	0.900
ENSACLP00000006507	ENSACLP00000006546	ENSACLP00000006507	ENSACLP00000006546	Uncharacterized protein.	Uncharacterized protein.	0.899
ENSACLP00000006507	ENSACLP00000006557	ENSACLP00000006507	ENSACLP00000006557	Uncharacterized protein.	HECT domain-containing protein.	0.899
ENSACLP00000006507	ENSACLP00000009816	ENSACLP00000006507	ENSACLP00000009816	Uncharacterized protein.	Neuralized E3 ubiquitin protein ligase 4.	0.806
ENSACLP00000006507	ENSACLP00000013582	ENSACLP00000006507	ENSACLP00000013582	Uncharacterized protein.	Uncharacterized protein.	0.839
ENSACLP00000006507	LOC113007418	ENSACLP00000006507	ENSACLP00000030257	Uncharacterized protein.	RAN binding protein 2.	0.774
ENSACLP00000006507	LOC113018712	ENSACLP00000006507	ENSACLP00000007040	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.765
ENSACLP00000006507	RNF8	ENSACLP00000006507	ENSACLP00000035704	Uncharacterized protein.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.875
ENSACLP00000006507	UBE3A	ENSACLP00000006507	ENSACLP00000010931	Uncharacterized protein.	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	0.812
ENSACLP00000006507	mapk6	ENSACLP00000006507	ENSACLP00000027932	Uncharacterized protein.	Mitogen-activated protein kinase 6.	0.747