Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000006515Subcommissural organ spondin. (5000 aa)    
Predicted Functional Partners:
adamts13
ADAM metallopeptidase with thrombospondin type 1 motif, 13.
    
 0.957
gp1bb
Glycoprotein Ib platelet subunit beta.
    
 0.938
ENSACLP00000002194
LRRCT domain-containing protein.
    
 0.925
itga8
Integrin, alpha 8; Belongs to the integrin alpha chain family.
    
 0.897
ENSACLP00000031964
Integrin beta; Belongs to the integrin beta chain family.
    
 0.894
itgb5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.893
ENSACLP00000029444
LRRCT domain-containing protein.
    
 0.890
ENSACLP00000029459
Si:ch211-117l17.7.
    
 0.889
LOC113010138
Integrin beta; Belongs to the integrin beta chain family.
    
 0.880
itgb1
Integrin beta; Belongs to the integrin beta chain family.
    
 0.880
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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