Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tango2Transport and golgi organization 2 homolog (Drosophila). (275 aa)    
Predicted Functional Partners:
mrpl40
Mitochondrial ribosomal protein L40.
      
 0.723
timm21
Translocase of inner mitochondrial membrane 21.
      
 0.714
ENSACLP00000033451
tRNA methyltransferase O.
     
 0.706
txnrd2
Thioredoxin reductase 2, tandem duplicate 1.
    
 
 0.688
top3b
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
      
 0.666
ENSACLP00000003813
Minichromosome maintenance complex component 3 associated protein.
      
 0.664
dgcr2
DiGeorge syndrome critical region gene 2.
      
 0.659
ENSACLP00000027567
Cytochrome c oxidase assembly factor COX18.
      
 0.659
ess2
Ess-2 splicing factor homolog.
      
 0.658
tomm22
Translocase of outer mitochondrial membrane 22 homolog (yeast).
      
 0.656
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.