Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
traddTnfrsf1a-associated via death domain. (330 aa)    
Predicted Functional Partners:
LOC113032516
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.999
LOC113031642
Tumor necrosis factor b (TNF superfamily, member 2).
    
 0.996
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.996
LOC113025693
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.990
LOC113033094
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.987
LOC113025455
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.987
LOC113008263
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.986
ENSACLP00000024870
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.985
ENSACLP00000025126
Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.985
LOC113011134
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.985
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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