Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRIT2Leucine rich repeat, Ig-like and transmembrane domains 2. (555 aa)    
Predicted Functional Partners:
lrit1
Leucine-rich repeat, immunoglobulin-like and transmembrane domains 1b.
   
 0.733
LOC113035014
Leucine-rich repeat, immunoglobulin-like and transmembrane domains 1a.
   
 0.733
LOC113022754
Tankyrase_bdg_C domain-containing protein.
    
  0.714
ccdc126
Coiled-coil domain containing 126.
      
 0.699
ENSACLP00000007109
WD repeat domain 17.
      
 0.693
LOC113025125
Family with sequence similarity 169 member B.
    
 
 0.683
ENSACLP00000005089
Uncharacterized protein.
      
 0.655
serpine3
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3; Belongs to the serpin family.
     
 0.652
ENSACLP00000019085
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28.
    
 0.629
MANSC4
MANSC domain containing 4.
      
 0.612
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: medium (78%) [HD]