Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ENSACLP00000006583Hyperpolarization activated cyclic nucleotide-gated potassium channel 1. (867 aa)    
Predicted Functional Partners:
ENSACLP00000030515
Cyclic nucleotide-binding domain-containing protein.
  
  
 
0.735
LOC113014953
XK-related protein.
     
  0.649
ENSACLP00000037203
XK-related protein.
     
  0.649
LOC113015665
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 0.589
LOC113036155
RAB guanine nucleotide exchange factor (GEF) 1, like.
     
  0.571
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1.
     
  0.571
LOC113033890
Uncharacterized protein.
     
  0.571
ENSACLP00000010450
Cyclic nucleotide-binding domain-containing protein.
  
  
 
0.547
ENSACLP00000003296
Cyclic nucleotide-binding domain-containing protein.
  
  
 
0.546
HCN2
Hyperpolarization activated cyclic nucleotide-gated potassium channel 2b.
  
  
 
0.546
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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