Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccbe1Collagen and calcium binding EGF domains 1. (399 aa)    
Predicted Functional Partners:
vegfc
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
    
 0.884
adamts14
ADAM metallopeptidase with thrombospondin type 1 motif, 14.
      
 0.696
SOX18
SRY-box transcription factor 18.
      
 0.693
lyve1
Lymphatic vessel endothelial hyaluronic receptor 1a.
     
 0.672
phf5a
PHD finger protein 5A.
      
 0.659
suclg2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
      
 0.658
itga9
Integrin, alpha 9; Belongs to the integrin alpha chain family.
    
 0.637
ENSACLP00000015432
Epidermal growth factor.
    
 0.597
tnfrsf13b
TACI-CRD2 domain-containing protein.
    
 0.575
vegfd
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
    
 0.539
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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