Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
optnOptineurin. (528 aa)    
Predicted Functional Partners:
tbk1
TANK-binding kinase 1.
    
 0.989
ENSACLP00000003770
TNFAIP3 interacting protein 1.
    
 0.988
ikbke
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.988
LOC113031642
Tumor necrosis factor b (TNF superfamily, member 2).
    
 0.988
sqstm1
Sequestosome 1.
    
 0.984
ENSACLP00000009605
Ubiquitin B.
    
 0.980
LOC113030103
Uncharacterized protein.
    
 0.980
ENSACLP00000021832
Huntingtin.
    
 
 0.979
map1lc3a
Microtubule-associated protein 1 light chain 3 alpha.
   
 0.977
map1lc3b
Microtubule-associated protein 1 light chain 3 beta.
   
 0.977
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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