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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
optnOptineurin. (528 aa)    
Predicted Functional Partners:
tbk1
TANK-binding kinase 1.
    
 0.984
ikbke
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.982
bcl10
BCL10 immune signaling adaptor.
    
 0.968
ENSACLP00000037094
Im:7152348.
    
 0.960
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.952
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.952
LOC113031642
Tumor necrosis factor b (TNF superfamily, member 2).
    
 0.943
ripk4
Receptor-interacting serine-threonine kinase 4.
    
 0.938
RPS27A
Ribosomal protein S27a.
   
 0.935
gabarap
GABA(A) receptor-associated protein b.
   
 0.930
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.