ENSACLP00000006726 protein (Astatotilapia calliptera)

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Score

ENSACLP00000006726

HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4112 aa)

Predicted Functional Partners:

RPS27A

0.986

uba52

0.985

ENSACLP00000006599

0.983

usp7

0.978

ENSACLP00000009605

0.976

LOC113030103

0.976

ambra1

0.976

LOC113018712

0.973

phax

0.973

faf2

0.958

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000006599	ENSACLP00000006726	ENSACLP00000006599	ENSACLP00000006726	MCL1 apoptosis regulator, BCL2 family member b.	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	0.983
ENSACLP00000006599	LOC113018712	ENSACLP00000006599	ENSACLP00000007040	MCL1 apoptosis regulator, BCL2 family member b.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.958
ENSACLP00000006726	ENSACLP00000006599	ENSACLP00000006726	ENSACLP00000006599	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	MCL1 apoptosis regulator, BCL2 family member b.	0.983
ENSACLP00000006726	ENSACLP00000009605	ENSACLP00000006726	ENSACLP00000009605	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Ubiquitin B.	0.976
ENSACLP00000006726	LOC113018712	ENSACLP00000006726	ENSACLP00000007040	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.973
ENSACLP00000006726	LOC113030103	ENSACLP00000006726	ENSACLP00000014166	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Uncharacterized protein.	0.976
ENSACLP00000006726	RPS27A	ENSACLP00000006726	ENSACLP00000004031	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Ribosomal protein S27a.	0.986
ENSACLP00000006726	ambra1	ENSACLP00000006726	ENSACLP00000032532	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Autophagy/beclin-1 regulator 1b.	0.976
ENSACLP00000006726	faf2	ENSACLP00000006726	ENSACLP00000003162	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Fas associated factor family member 2.	0.958
ENSACLP00000006726	phax	ENSACLP00000006726	ENSACLP00000017879	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Phosphorylated adaptor for RNA export.	0.973
ENSACLP00000006726	uba52	ENSACLP00000006726	ENSACLP00000032826	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.985
ENSACLP00000006726	usp7	ENSACLP00000006726	ENSACLP00000015131	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.978
ENSACLP00000009605	ENSACLP00000006726	ENSACLP00000009605	ENSACLP00000006726	Ubiquitin B.	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	0.976
ENSACLP00000009605	LOC113018712	ENSACLP00000009605	ENSACLP00000007040	Ubiquitin B.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.933
ENSACLP00000009605	RPS27A	ENSACLP00000009605	ENSACLP00000004031	Ubiquitin B.	Ribosomal protein S27a.	0.996
ENSACLP00000009605	faf2	ENSACLP00000009605	ENSACLP00000003162	Ubiquitin B.	Fas associated factor family member 2.	0.582
ENSACLP00000009605	uba52	ENSACLP00000009605	ENSACLP00000032826	Ubiquitin B.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.997
ENSACLP00000009605	usp7	ENSACLP00000009605	ENSACLP00000015131	Ubiquitin B.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.952
LOC113018712	ENSACLP00000006599	ENSACLP00000007040	ENSACLP00000006599	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	MCL1 apoptosis regulator, BCL2 family member b.	0.958
LOC113018712	ENSACLP00000006726	ENSACLP00000007040	ENSACLP00000006726	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	0.973