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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000006726HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4112 aa)    
Predicted Functional Partners:
ENSACLP00000006599
MCL1 apoptosis regulator, BCL2 family member b.
    
 
 0.952
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.950
RPS27A
Ribosomal protein S27a.
   
 0.921
ddit4
DNA-damage-inducible transcript 4.
    
   0.917
ENSACLP00000009605
Ubiquitin B.
   
 0.910
LOC113030103
Uncharacterized protein.
   
 0.910
snrnp200
Small nuclear ribonucleoprotein 200 (U5).
   
 
 0.814
trip12
Thyroid hormone receptor interactor 12.
   
 
0.807
ENSACLP00000033160
Ubiquitin protein ligase E3 component n-recognin 4.
   
 
 0.790
setd5
SET domain containing 5.
   
   0.785
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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