Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113023512IRS-type PTB domain-containing protein. (483 aa)    
Predicted Functional Partners:
LOC113036661
CRK proto-oncogene, adaptor protein.
    
 0.611
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.611
LOC113030677
Uncharacterized protein.
    
 0.611
LOC113024435
GRB2 related adaptor protein b.
    
 0.575
ENSACLP00000011894
GRB2 related adaptor protein 2b.
    
 0.575
LOC113021048
GRB2 related adaptor protein a.
    
 0.575
grb2
Growth factor receptor-bound protein 2b.
    
 0.575
LOC113020258
Uncharacterized protein.
    
 0.575
LOC113020262
GRB2 related adaptor protein 2a.
    
 0.575
ENSACLP00000019486
Protein tyrosine phosphatase non-receptor type 11b.
    
 0.554
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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