Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000006875Pyrin domain-containing protein. (97 aa)    
Predicted Functional Partners:
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
  0.735
LOC113036202
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
  0.590
LOC113030401
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
    
  0.590
LOC113024821
Proline-serine-threonine phosphatase interacting protein 1b.
    
  0.578
LOC113026793
Proline-serine-threonine phosphatase interacting protein 1a.
    
  0.578
LOC113019113
Receptor-interacting serine-threonine kinase 3.
    
  0.516
ENSACLP00000037208
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
  0.516
LOC113026884
Uncharacterized protein.
    
  0.516
ENSACLP00000017060
Uncharacterized protein; Belongs to the peptidase C14A family.
    
  0.483
ENSACLP00000024366
CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.
    
  0.483
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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