Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
snx8Sorting nexin 8a. (516 aa)    
Predicted Functional Partners:
msh3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
    
   0.974
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.934
ENSACLP00000002778
Insulin-like growth factor 2 receptor.
    
 0.906
snx5
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.849
snx6
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.843
hoga1
4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family.
    
  0.791
npl
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); Belongs to the DapA family.
    
  0.791
kars1
Lysine--tRNA ligase.
    
   0.773
nanp
N-acetylneuraminic acid phosphatase.
     
  0.773
ENSACLP00000025811
U3snoRNP10 domain-containing protein.
    
   0.754
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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