Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)    
Predicted Functional Partners:
fgfr2
Fibroblast growth factor receptor.
    
 0.989
LOC113033119
Fibroblast growth factor receptor.
    
 0.984
ENSACLP00000029128
Uncharacterized protein.
    
 0.984
fgfr3
Fibroblast growth factor receptor.
    
 0.980
ENSACLP00000023118
Fibroblast growth factor receptor 4; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.980
ENSACLP00000029170
Uncharacterized protein.
    
 0.973
LOC113026317
Fibroblast growth factor receptor.
    
 0.973
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.958
fgf3
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
 
 0.945
ENSACLP00000013202
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.924
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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