Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC113015050Organic solute carrier partner 1a. (388 aa)    
Predicted Functional Partners:
wdr54
WD repeat domain 54.
   
   0.903
usp16
Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
    
   0.721
LSM10
LSM10, U7 small nuclear RNA associated.
   
  
 0.676
arl14ep
ADP-ribosylation factor-like 14 effector protein.
      
 0.654
stk40
Serine/threonine kinase 40.
      
 0.654
LOC113011980
Glycogenin 1a.
    
   0.608
LOC113015879
Glycogenin 2.
    
   0.608
psmd3
Proteasome 26S subunit, non-ATPase 3.
      
 0.608
mrps15
Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.
      
 0.593
usp45
Ubiquitin carboxyl-terminal hydrolase.
    
   0.492
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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