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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpgd15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)    
Predicted Functional Partners:
hsdl2
Hydroxysteroid dehydrogenase like 2.
  
 0.858
ENSACLP00000028811
Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family.
  
 0.833
ENSACLP00000009358
Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.832
hibch
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.825
oxct1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.825
LOC113018843
Dehydrogenase/reductase (SDR family) member 4.
  
  
 
0.817
acox3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.812
acox1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.811
aacs
Acetoacetyl-CoA synthetase.
    
 0.807
ENSACLP00000041285
Prostaglandin E synthase.
     
 0.797
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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