Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
parnPoly(A)-specific ribonuclease (deadenylation nuclease). (677 aa)    
Predicted Functional Partners:
dhx37
DEAH (Asp-Glu-Ala-His) box polypeptide 37.
    
 
 0.975
dcp2
Decapping mRNA 2.
     
 0.973
bysl
Bystin-like.
   
   0.936
fam207a
Family with sequence similarity 207 member A.
    
   0.934
xrn1
5'-3' exoribonuclease 1.
    
 
 0.920
UTP14C
UTP14C small subunit processome component.
    
   0.882
tsr1
TSR1 ribosome maturation factor.
    
 
 0.837
snupn
Snurportin 1.
    
 
 0.825
dis3l2
DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
     
 0.817
exosc4
Exosome component 4.
    
 0.787
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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