STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cblbCbl proto-oncogene B, E3 ubiquitin protein ligase. (935 aa)    
Predicted Functional Partners:
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.960
LOC113022284
Macrophage stimulating 1 receptor a.
    
 0.960
mst1r
Macrophage stimulating 1 receptor b.
    
 0.960
syk
Tyrosine-protein kinase.
    
 0.954
LOC113010022
Receptor protein-tyrosine kinase.
    
 0.949
SH2B2
SH2B adaptor protein 2.
    
 0.949
LOC113029559
Receptor protein-tyrosine kinase.
    
 0.949
sh3kbp1
SH3-domain kinase binding protein 1.
    
 0.948
grb2
Growth factor receptor-bound protein 2b.
    
 0.944
ENSACLP00000008280
Cbl-PTB domain-containing protein.
    
  0.929
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.