cop1 protein (Astatotilapia calliptera) - STRING interaction network

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Score

cop1

COP1 E3 ubiquitin ligase. (715 aa)

Predicted Functional Partners:

LOC113018712

0.996

det1

0.994

ddb1

0.992

LOC113022113

0.978

ENSACLP00000008409

0.975

etv5

0.975

rbx1

0.974

stk40

0.974

etv4

0.968

ddb2

0.962

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000008409	LOC113018712	ENSACLP00000008409	ENSACLP00000007040	Ets variant 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.675
ENSACLP00000008409	cop1	ENSACLP00000008409	ENSACLP00000007039	Ets variant 1.	COP1 E3 ubiquitin ligase.	0.975
ENSACLP00000008409	det1	ENSACLP00000008409	ENSACLP00000030950	Ets variant 1.	DET1 partner of COP1 E3 ubiquitin ligase.	0.915
ENSACLP00000008409	etv5	ENSACLP00000008409	ENSACLP00000032105	Ets variant 1.	Ets variant 5a.	0.810
ENSACLP00000008409	stk40	ENSACLP00000008409	ENSACLP00000041361	Ets variant 1.	Serine/threonine kinase 40.	0.974
LOC113018712	ENSACLP00000008409	ENSACLP00000007040	ENSACLP00000008409	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ets variant 1.	0.675
LOC113018712	LOC113022113	ENSACLP00000007040	ENSACLP00000005220	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Tribbles pseudokinase 3.	0.471
LOC113018712	cop1	ENSACLP00000007040	ENSACLP00000007039	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	COP1 E3 ubiquitin ligase.	0.996
LOC113018712	ddb1	ENSACLP00000007040	ENSACLP00000018313	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Damage-specific DNA binding protein 1.	0.744
LOC113018712	ddb2	ENSACLP00000007040	ENSACLP00000020982	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Damage-specific DNA binding protein 2.	0.975
LOC113018712	rbx1	ENSACLP00000007040	ENSACLP00000020852	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ring-box 1, E3 ubiquitin protein ligase.	0.882
LOC113022113	LOC113018712	ENSACLP00000005220	ENSACLP00000007040	Tribbles pseudokinase 3.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.471
LOC113022113	cop1	ENSACLP00000005220	ENSACLP00000007039	Tribbles pseudokinase 3.	COP1 E3 ubiquitin ligase.	0.978
LOC113022113	det1	ENSACLP00000005220	ENSACLP00000030950	Tribbles pseudokinase 3.	DET1 partner of COP1 E3 ubiquitin ligase.	0.626
LOC113022113	stk40	ENSACLP00000005220	ENSACLP00000041361	Tribbles pseudokinase 3.	Serine/threonine kinase 40.	0.976
cop1	ENSACLP00000008409	ENSACLP00000007039	ENSACLP00000008409	COP1 E3 ubiquitin ligase.	Ets variant 1.	0.975
cop1	LOC113018712	ENSACLP00000007039	ENSACLP00000007040	COP1 E3 ubiquitin ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.996
cop1	LOC113022113	ENSACLP00000007039	ENSACLP00000005220	COP1 E3 ubiquitin ligase.	Tribbles pseudokinase 3.	0.978
cop1	ddb1	ENSACLP00000007039	ENSACLP00000018313	COP1 E3 ubiquitin ligase.	Damage-specific DNA binding protein 1.	0.992
cop1	ddb2	ENSACLP00000007039	ENSACLP00000020982	COP1 E3 ubiquitin ligase.	Damage-specific DNA binding protein 2.	0.962