Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113023392E2F_TDP domain-containing protein. (307 aa)    
Predicted Functional Partners:
tfdp1
Transcription factor.
   
 0.965
rb1
Retinoblastoma 1.
   
 0.947
ENSACLP00000025268
Retinoblastoma-like 1 (p107).
   
 0.947
LOC113025000
Retinoblastoma-like 2 (p130).
   
 0.947
LOC113025730
Mothers against decapentaplegic homolog.
    
 0.881
LOC113033624
Mothers against decapentaplegic homolog.
    
 0.881
ENSACLP00000016742
E2F transcription factor 4.
     
  0.871
ENSACLP00000022602
Mothers against decapentaplegic homolog.
    
 0.860
LOC113014376
Mothers against decapentaplegic homolog.
    
 0.860
LOC113033248
Mothers against decapentaplegic homolog.
    
 0.812
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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