Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000007199Plexin_cytopl domain-containing protein. (295 aa)    
Predicted Functional Partners:
nrp1
Neuropilin; Belongs to the neuropilin family.
    
 0.963
sema3e
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family.
    
 0.834
ENSACLP00000009988
Uncharacterized protein; Belongs to the semaphorin family.
    
 0.814
rnd1
Rho family GTPase 1b.
    
 0.797
rnd3
Rho family GTPase 3a.
    
 0.797
sema3b
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family.
    
 0.796
LOC113008718
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.
    
 0.794
ENSACLP00000036195
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family.
    
 0.794
sema7a
Semaphorin 7A; Belongs to the semaphorin family.
    
 0.790
ENSACLP00000027732
Sema domain-containing protein; Belongs to the semaphorin family.
    
 0.790
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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