Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113015285Four and a half LIM domains 3b. (279 aa)    
Predicted Functional Partners:
ENSACLP00000002595
Regulatory factor X, 1a (influences HLA class II expression).
    
 
 0.912
zbtb18
Zinc finger and BTB domain containing 18.
    
 
 0.704
dvl2
Dishevelled segment polarity protein 2.
    
 0.586
dvl3
Dishevelled segment polarity protein 3a.
    
 0.586
rnpepl1
Arginyl aminopeptidase like 1.
    
 0.586
ENSACLP00000003757
Vang-like protein.
    
 0.567
VANGL2
Vang-like protein.
    
 0.567
LOC113008135
Vang-like protein.
    
 0.567
VANGL1
Vang-like protein.
    
 0.567
LOC113022754
Tankyrase_bdg_C domain-containing protein.
    
 
 0.524
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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