STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000007289Uncharacterized protein. (389 aa)    
Predicted Functional Partners:
ENSACLP00000006066
BUB3 mitotic checkpoint protein.
    
 0.633
ENSACLP00000018362
Serine/threonine-protein kinase TOR.
   
 0.615
LOC113007866
Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family.
    
 0.596
LOC113022608
Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
    
 0.596
ENSACLP00000016234
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
   
  0.596
LOC113016569
Si:ch211-113j14.1; Belongs to the cytochrome P450 family.
    
 0.596
ENSACLP00000023092
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
   
  0.596
LOC113026744
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
    
 0.596
ENSACLP00000030400
Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
    
 0.596
ENSACLP00000030567
Si:dkey-91i10.3; Belongs to the cytochrome P450 family.
    
 0.596
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.