close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ddit4DNA-damage-inducible transcript 4. (225 aa)    
Predicted Functional Partners:
ENSACLP00000030835
TSC complex subunit 2.
     
 0.925
ENSACLP00000006726
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
   0.917
tsc1
TSC complex subunit 1b.
   
 
 0.871
ENSACLP00000012749
Uncharacterized protein.
   
 
 0.869
LOC113009124
TBC1 domain family, member 7.
     
 0.865
LOC113035061
Uncharacterized protein.
  
  
 
0.853
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1.
    
   0.804
LOC113036202
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
   
  0.715
LOC113030401
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
   
  0.715
LOC113036694
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family.
   
  0.705
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.