Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000007302SREBF chaperone. (1271 aa)    
Predicted Functional Partners:
ENSACLP00000031908
Membrane-bound transcription factor peptidase, site 1.
     
 0.978
srebf2
Sterol regulatory element binding transcription factor 2.
    
 0.971
srebf1
Sterol regulatory element binding transcription factor 1.
    
 0.970
insig2
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.
    
 0.945
insig1
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.
    
 0.945
ENSACLP00000035355
Niemann-Pick disease, type C2.
    
 0.928
ENSACLP00000031450
MYCN proto-oncogene, bHLH transcription factor.
    
 0.752
mbtps2
Membrane-bound transcription factor peptidase, site 2.
      
 0.726
ENSACLP00000003828
ER lipid raft associated 2.
    
 
 0.709
erlin1
ER lipid raft associated 1.
    
 
 0.709
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.