STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000007302SREBF chaperone. (1271 aa)    
Predicted Functional Partners:
srebf2
Sterol regulatory element binding transcription factor 2.
   
 0.977
srebf1
Sterol regulatory element binding transcription factor 1.
   
 0.977
ENSACLP00000035355
Niemann-Pick disease, type C2.
   
 0.969
insig2
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.
   
 0.936
insig1
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.
   
 0.936
ENSACLP00000031450
MYCN proto-oncogene, bHLH transcription factor.
   
 0.908
ENSACLP00000031908
Membrane-bound transcription factor peptidase, site 1.
   
 
 0.817
OSBPL10
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.597
osbpl11
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.597
OSBPL8
Oxysterol-binding protein; Belongs to the OSBP family.
   
 0.592
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.