Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
afap1Actin filament associated protein 1. (819 aa)    
Predicted Functional Partners:
gadd45g
Growth arrest and DNA-damage-inducible, gamma a.
    
   0.721
txnrd2
Thioredoxin reductase 2, tandem duplicate 1.
      
 0.656
ENSACLP00000036012
GDP-mannose 4,6-dehydratase.
      
 0.649
tmco1
Transmembrane and coiled-coil domains 1.
      
 0.611
lrp12
Low density lipoprotein receptor-related protein 12.
      
 0.600
ENSACLP00000030550
Growth arrest-specific 7a.
     
 0.532
gas7
Growth arrest specific 7.
     
 0.532
fndc3b
Fibronectin type III domain containing 3Ba.
      
 0.501
LOC113021239
ZP domain-containing protein.
      
 0.494
tgfbr3
Transforming growth factor, beta receptor III.
      
 0.494
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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