Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000007400Zgc:110239; Belongs to the peptidase C1 family. (555 aa)    
Predicted Functional Partners:
ENSACLP00000015540
Cathepsin O; Belongs to the peptidase C1 family.
    
 0.573
LOC113033302
Cathepsin F; Belongs to the peptidase C1 family.
    
 0.573
ENSACLP00000002967
Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.
   
 0.552
cd74
CD74 molecule, major histocompatibility complex, class II invariant chain a.
   
 0.552
LOC113023368
Carboxypeptidase; Belongs to the peptidase S10 family.
   
 0.486
ctsa
Carboxypeptidase; Belongs to the peptidase S10 family.
   
 0.486
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.486
grn
Granulin b.
   
 0.471
ENSACLP00000033495
Granulin a.
   
 0.471
ENSACLP00000033585
GRANULINS domain-containing protein.
   
 0.471
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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