STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1249 aa)    
Predicted Functional Partners:
RPS27A
Ribosomal protein S27a.
    
 0.937
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.894
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.889
fgfr2
Fibroblast growth factor receptor.
    
  0.885
LOC113010022
Receptor protein-tyrosine kinase.
    
 0.884
LOC113029559
Receptor protein-tyrosine kinase.
    
 0.883
LOC113014950
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.882
SGK1
Non-specific serine/threonine protein kinase.
    
 0.882
sgk2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.882
ENSACLP00000031071
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.879
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.