Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sbno2Strawberry notch homolog 2. (1580 aa)    
Predicted Functional Partners:
cdk2ap2
Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family.
     
 0.778
CDK2AP1
Cyclin dependent kinase 2 associated protein 1.
     
 0.778
LOC113035508
Interleukin 22 receptor, alpha 2.
      
 0.657
vgll2
Vestigial-like family member 2a.
    
   0.630
ENSACLP00000006316
Nucleolar protein 8.
      
 0.528
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
      
 0.526
ENSACLP00000028680
Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
    
   0.525
sox5
SRY-box transcription factor 5.
      
 0.517
LOC113017525
Galactose-3-O-sulfotransferase 4.
      
 0.500
ttc26
Tetratricopeptide repeat domain 26.
      
 0.490
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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