Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prlrProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily. (632 aa)    
Predicted Functional Partners:
LOC113020086
Uncharacterized protein.
    
 0.992
LOC113020087
Prolactin.
    
 0.992
ENSACLP00000021296
Prolactin 2.
    
 0.992
ENSACLP00000001294
Somatolactin alpha.
   
 0.967
LOC113019958
Growth hormone 1.
   
 0.967
lepr
Leptin receptor.
     
 0.957
LOC113033249
Tyrosine-protein kinase.
    
 0.952
LOC113025906
Tyrosine-protein kinase.
    
 0.952
LOC113027743
Signal transducer and activator of transcription.
    
 0.944
LOC113020422
Signal transducer and activator of transcription.
    
 0.944
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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