Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
zfand2aZinc finger, AN1-type domain 2A. (279 aa)    
Predicted Functional Partners:
psmd6
Proteasome 26S subunit, non-ATPase 6.
   
   0.911
psmc6
Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.
   
   0.908
psmc5
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
   
 
 0.881
ENSACLP00000039640
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
 
 0.831
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 
 0.818
psmc3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
   
   0.809
psmd3
Proteasome 26S subunit, non-ATPase 3.
   
   0.804
psmd12
Proteasome 26S subunit, non-ATPase 12.
   
   0.802
psmc4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
   
   0.801
ENSACLP00000001728
Uncharacterized protein.
     
  0.800
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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