Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptpaSerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (343 aa)    
Predicted Functional Partners:
ppp4r2
Protein phosphatase 4, regulatory subunit 2b.
   
 
 0.989
LOC113036096
Protein phosphatase 2, regulatory subunit A, beta b.
   
 0.978
ppp4r3a
SMEK homolog 1, suppressor of mek1 (Dictyostelium).
    
 
 0.975
ppp4c
Serine/threonine-protein phosphatase.
    
 
 0.955
lcmt1
Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.
    
 
 0.938
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.900
LOC113030100
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.900
ENSACLP00000023703
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.900
LOC113034924
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.900
akt2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.900
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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