Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
chaf1bChromatin assembly factor 1, subunit B. (600 aa)    
Predicted Functional Partners:
ENSACLP00000008291
Chromatin assembly factor 1, subunit A (p150).
   
 0.998
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.960
LOC113020617
Anti-silencing function 1Ba histone chaperone.
   
 
 0.944
ENSACLP00000035523
Anti-silencing function 1Ba histone chaperone.
   
 
 0.944
LOC113027513
Retinoblastoma binding protein 4, like.
   
 
 0.896
LOC113011815
Retinoblastoma binding protein 4.
   
 
 0.896
LOC113014472
WD_REPEATS_REGION domain-containing protein.
   
 
 0.896
mcm5
DNA helicase; Belongs to the MCM family.
   
  
 0.894
insig2
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.
   
 
 0.884
insig1
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis.
   
 
 0.884
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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