Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000007698EBP like. (223 aa)    
Predicted Functional Partners:
dhcr24
24-dehydrocholesterol reductase.
   
 0.917
ENSACLP00000032963
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 
 0.882
dhcr7
7-dehydrocholesterol reductase.
   
 
 0.868
LOC113027168
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 
 0.847
atp6v1f
V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
   
 
 0.798
tm7sf2
Transmembrane 7 superfamily member 2.
   
 
 0.775
lbr
Lamin B receptor.
   
 
 0.775
LOC113016200
Hydroxysteroid (17-beta) dehydrogenase 7.
   
 
 0.770
LOC113010628
Uncharacterized protein.
   
 
 0.770
atp6v0d1
V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.
    
 
 0.759
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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